Fatty Acid Binding Protein (FABP) Modulation as a Novel Therapeutic Strategy
Time: 2:30 pm
day: Day Two
Details:
- Reviewing how FABPs, particular FABP5, are intracellular carrier proteins of endocannnabinoids, and inhibiting FABP5 decreases endocannabinoid uptake and increases endocannabinoid levels
- Introduction to ART26.12, the IND-approved lead small molecule FABP5, being developed for pain indications and the involvement of cannabinoid receptor activation in its analgesic effects
- The broader therapeutic utility of inhibiting FABP5 and other FABP isoforms
